SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1443688189391ab4bd120a27b912765e745a73b80eaa41817fa4ad41a58916a9' 
  AND token = 'y0vS+auYF0Gep9r6Y1J1CXcRJgrKWSubk+4ZjlchBwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}