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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea374db19638841b2f88e851f82e835cadd68771ebfa53e1eabf84de6776c489' 
  AND token = 'd3j1ehhAQS6zFCrcyCgpO22wfjDGcA06InWM4t6utRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}