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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b5ec68d0d9c2870153cef9b8febf22a799d6011e33eeea883b89cc006bee67' 
  AND token = 'XdBp64cQBBOJDuD0q75pzfIRktEfjsGwV9TEFL84yLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}