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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9f52a16d1396ddf8dbdd5bfc06731d0a7586b3705cfa12dfdd0dbaa7a0bb312' 
  AND token = '8oyvAh2JKq4kUgaa5JMweAAtpqceBGsxmBasdk2y3cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}