SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a85270cefb5b6837123f619443b97c89884430bf0169e042630f67f326f819' 
  AND token = 'A/4FsI0VYeHwqwFCjoQHIWj2qSzjn4oU/BQV61snhMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}