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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3878686b7825517539e1a87ecb590256be9c86d85e46e23ad31a94143f79602' 
  AND token = 'lCNFTXoIYJRHl2EaNpDmJjCRcl4CWWRQdRxtpTfai+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}