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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e6d3e29b92975b435bbc53e6788fa9f81b62c6d353e3fd5e79afaf12a93449' 
  AND token = 'rqX+28nJ3b2kS3qOhnBiR2IN8cxxSCTzX3f04jxxU2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}