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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81033ba9e1259b19d5fc0bc350fcb853b3d8a14e315386679e446bcf26b41e00' 
  AND token = 'tJ7nvFcHbJ7o62EAndigj/t0lQYqbJRr7HMys8r68kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}