SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f5f0ed50b821fef1e347927297a9bbb70035a10b7eab1bfa121e68c6fe1e00' 
  AND token = 'h0xpURqaOAALV+HaDQEDHmxiHt2yhlkJLulLPhYD+58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}