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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8ad48aeb03803adda657153cfbfc59cebeef27271f2bc17b693f4dd94c4b40' 
  AND token = 'mQFmEX8kgML0mxJipRCPxcynW5khEx2M6jQkTWUePq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}