SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a62f2a226c3aedb7367f1e16202e96735b80f2527070194e052caa2c6cc4dd' 
  AND token = '0gS0xl8owbYGRpPKfcXo0cX2oJ+8+OEHuGQpqINLtP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}