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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df6c2a1166f4f827a1dd6ffd31c6020c7e545ff53a2134626ced15dabb9f20e' 
  AND token = 'i2swbfVBnvZzveJ3jQqlM462RveT5pDIhWy/hUQBjzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}