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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4073d75eb203024c69e19bbb7f2a270276f7bef154044485b1590f5069b10bf1' 
  AND token = 'WNUIFjJ1EOXbKipmxnR03HZeKcz4CYMYWFSiSJ6zT9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}