SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781c2665962f1a1041f0f6c6e11196af0ef0c8870c89804a7e5c66bf7c10c36e' 
  AND token = 'EuZJ56tu+EB5X8h0fTvym4f/PeN8WmSuAghku/PXMUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}