SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac879268588da6d52189d1d9de1c944215672129344ba41413b92ec9c14debf' 
  AND token = 'kmTQnWldk64UZLnyaWx1/wB2ojO6bXaM76E9rpqKOkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}