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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29806b22fce371c3987e1d76b7d81376e48b46602bcf293a3f66fe5ef5819c86' 
  AND token = 'KWfZ0V2/lP5kfdc3q2n3P6S84bHyAEOWV4B9mU9XEtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}