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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0253286d90a0aab3b1e4fc98d188685180d81e7bf28fb15a21aa8b9670ecdaa0' 
  AND token = 'IZk+K6X3yOndMbc4+OgBvN3Db2FT7Ftz4Z8vAnfaOJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}