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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb6e5d5a73bc914437df4a465ff14af46f4c526a99cacc82a8adaf61fe8c527d' 
  AND token = 'zOXZENaX9btw9zMKLYNZa5/KGZZDMWCXJhk+AQ4gpcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}