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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00857215293f51712b57560b52a02ae1cdcbd7fe8936a1708ade139b79f49ce0' 
  AND token = 'NcMXsnjRQ9Tb+8tsnHNfRT3QWyA0kyZYvLcg0yT6lYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}