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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf3d614bade04c13360c303bbb73dbc48826ca094aef1dc7322582804077542' 
  AND token = '6yVAdBNA3d09neTnkf7h4mBzyGKId55AJ7C9t+i+tHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}