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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fe81baefaf024831a1de86828fe3f99c0db8d7eb00633c67ee4604bf1d7b34' 
  AND token = '82rZATevSOkWG/z6+MBqSuZar6rI29wCOzBxnQbf4RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}