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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4cebc12f3fa279fae0af7c27ab6a87f22549f165dfc54241cfd6cae9a04db8' 
  AND token = '6+PxYDNiQMynOW7pP+A/E4fpK7uddtjE1LY7fjBssZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}