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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7675b40024a5a840250b64d82f972a7ce77e54dcd40d6dffeb56b4982740291c' 
  AND token = 'I3yfnrBsxMIUyFExvjiFmxu9qiQWYBQw+k7KGWmJ5CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}