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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2ec083fa2242ca9098d07a7d3a83ad25e5fe2b4d3d9dbcfec5097a4128cd652' 
  AND token = 'WE23nyhcsd/HPPygdHpDDJVBRJDbPHGRibVRyJt2gNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}