SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e7791460f45044ec6e1b09fbd8e80b6679b80db4ccea39fdb8b2a5ad225ee5' 
  AND token = '6N6Sy7WLL/v3gE8fBJn+ctlnh0IclFmybghZ4UZFGn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}