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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c0709e27e58582cea2eb4ac54b8dc0a2b0fe73fb56ce54ce8f65365af8c013' 
  AND token = 'v/2WTT1uGXLBt+5QQSIoqqhMxNCRzceVs1P/i7xj3pI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}