SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e3b0b443d418bb78ac28f7f9bbf25719a666906cd53e261158c91412c1d4dd3' 
  AND token = '+WI6+3OkkB0pPmNsvNVylgrsiJzkiZQP9qwmaan9auc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}