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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11d6777b453b160e1dfb9a7e55de1a9ff3c5f4c87365ce753d15be9172c0bccf' 
  AND token = 'HinFhPQ7xk/8RDoNrSIqUWB0sThI07RAn5bWRCfncO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}