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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a621d59c45d89269a431ddb835bff4857c38ca5b2aa8bd446561b5b3d5aa1bf6' 
  AND token = 't5SppTudRw5BmBmsv/0v2q+Fm4t1J2tcIA1l96QLW60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}