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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24e70c899105ed5868b8aab19ac80abf2a18d197e43aea2560b8dbbf41aa6d50' 
  AND token = '2+eM9jbg4nTXNc1B2eDYdUKaY7eTzCoCD1dx2hrFvGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}