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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ea81cef4d914bfa62275e9cc28f29dd711a9c22d880419d60abbba2f2f351b' 
  AND token = 'HAXtYkD7/Y5y7zCtmmQfyS++epFXN3MZzXzSNoEfn8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}