SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '145c633c076a1bd11c248f746b168adee660105ccea84e7e7c55813448f0ef67' 
  AND token = 'cNl9rsbnTkMjgAGDDgLtb9haUAHzW1Roq5RvZkw+W4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}