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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49f77a173723571430b2c4710deac295967f3609d4cb472a2d29eb386248683' 
  AND token = 'aQr6+x5MJ0GjqsPu9KeykSsgRLNXmG6jsuyV0pHaQ1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}