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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b6810f83716a65ba460ace9ecbd8d1dce742a3f506afb9123e7bf99a3928e43' 
  AND token = '+YvtsGTcA/ts3rFPRzk3S++kivGTxkFSD/vgAftNk9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}