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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4daac9d8e885f69a8e6ffaa7ac526bb5292b24f4be4ec525030c91e4215a87fa' 
  AND token = 'cs0YuWFLJJk8YNT+qoSURzk7vDdCOMn0CVeAn3AoVmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}