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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2365f1a910dac17ce4ed871334052d5f1d659039ab2480a87fea5fe567e8e708' 
  AND token = '3RKJPTqN7f+mkyRw2hFlFVmMeC0mTkZR3/xVI6KTd5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}