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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb550c38e8e490771629348b75ec4ebf33027c9d6df4362717e71833faee19e9' 
  AND token = 'HMv8g+kduN8kXLaN6RIhpDK+mT3K23CMjMWMot4eibc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}