SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c68a614556faeec333e91c572812d47d3c9548f6f331c742a800a34fa2dab60' 
  AND token = 'P/rtjdCIWXwW7VEWIo4YZyiAad7QgPW6XvnmlBg6BmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}