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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33237f42702fcdc755b824bbd291da1ace7f6073f541cfe34aae8c4841997b02' 
  AND token = 'q+R2kOcTLuO9xpzOSHrfPfi0wSHE63AJhZPZGrdvyNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}