SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9305459efb01c6049e0da8e03aa1597cba8d416587e967a51d590741ab3ba118' 
  AND token = 'bQr8zjcLsYC+BTP33+ZNYeCjTLk3PDi3nDgH5BVQfqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00177

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}