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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d734c46ab631e4f2f8fa8e5ec69258727084829b653e56bb741ba2aa9723008' 
  AND token = 'jwiAUlZrMfJ/cA0Mn/d9yNP1OnWRXg+Ki/FOkQWz09o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}