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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0541fd9a7e99685b7c8f2b7db0925d1fe72ea3c9e72884e19b84b256a0a77d7' 
  AND token = 'MOoObMqx+4w8Bf6CiEpUG8xRMJAWKUoevrrjSuSOxgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}