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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eca27bf0d630c610831d80dd53a4dbdd86e92395a71656b8a5d813d8d856bda' 
  AND token = 'PzS5FIqAWvf/KL3efydoXZeu0+QdrdbE548D5PWezo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}