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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e6e006c8ab686953c09994348d0beb3c2f811a89ceba417adbe2cc99755de1' 
  AND token = 'jUMIZSN4RpJpUBQUEt+QrN82yDOFvW4Egr8OQIlrEAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}