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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f24993e1b5793c74621a0b1b0673c577733c96106d29b5b0b1601baf9292a238' 
  AND token = 'oCE6qiXq0gJCrD44rMHwrA2duNeESOVM7gwKiPtwl8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}