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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a111fe7b00f77d22a4b1b9f643392124101f98b90d746e6df6e92c38bb4e60a5' 
  AND token = 'k9AJ+C6NgUr8aetzd2s9bg5vEOv8rCIVpH+KKlGsqd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}