SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2edb39091d0a58dc82e7b43475ca7cdf1e04342b96b554789580abf643dba2' 
  AND token = 'GOWYonM8ivkFAa9ljR/hhSAi5OSXhViA8rSnRrNAFZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}