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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a406f37c47bec3bbb4306d7799b184f8fb10af2197d9061b21a745dbc5bc5f' 
  AND token = '1cB0341t+XdFMbgBDymcTVVRJJSNKVxYo2V8g7Gx+Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}