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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae90e7eff5910e8524ab73893be71c939eef5cbc093df28e4a1a0721c8eae5e3' 
  AND token = '+LDJ0VsmbTgG/5FVTPYqWjFUKi3TxguXfP2Ah/YJb3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}