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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8002b8750b34103f56dbb6393a9c876f36a562472bacbfe97a3f1e03bcbcc973' 
  AND token = 'osInNeqlVpiVn5fSna0HsyYRTGlOYVVt7/bvAS+/Wa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}